Reduced numbers of regulatory T cells in chronic heart failure seems not to be restored by cardiac resynchronization therapy

Table 2 Comparative analysis of overall T cells and their subsets in healthy individuals and patient groups

		HG (n = 11)	HG vs HFP-T0 P values	HFP (n = 39)		HG vs HFP-T6 P values
		HG (n = 11)	HG vs HFP-T0 P values	HFP-T0	HFP-T6	HG vs HFP-T6 P values
WBC	10³/ µl	7.52 ± 2.07	0.170	8.36 ± 1.71	8.34 ± 1.76	0.202
T cells	%	76.10 ± 9.50	0.513	77.39 ± 9.95	77.07 ± 10.73	0.699
T cells	Cells/µl	1510.45 ± 381.77	0.717	1467.14 ± 638.21	1481.90 ± 588.58	0.885
Th cells	%	66.22 ± 7.87	0.545	63.63 ± 10.85	61.99 ± 12.91	0.326
Th cells	Cells/µl	994.93 ± 258.20	0.331	919.55 ± 426.25	918.63 ± 383.68	0.449
Tc cells	%	28.78 ± 7.35	0.578	31.33 ± 10.84	33.67 ± 12.27	0.302
Tc cells	Cells/µl	439.63 ± 174.87	1.000	474.22 ± 274.04	519.76 ± 293.35	0.647

Results are expressed as mean ± standard deviation
Statistically significant differences were considered when P < 0.05 (Mann–Whitney U test and Wilcoxon signed-rank)
Th T helper (CD4⁺) cells, Tc T cytotoxic (CD8⁺) cells, HG healthy control group, HFP heart failure patients, HFP-T0 (T0) baseline assessment, HFP-T6 (T6) follow-up evaluation, 6 months after Cardiac Resynchronization Therapy (CRT), WBC white blood cells

ISSN: 1471-2261