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Table 3 Comparative analysis of overall T cells and their subsets in patient groups, according to response to CRT

From: Reduced numbers of regulatory T cells in chronic heart failure seems not to be restored by cardiac resynchronization therapy

  

HFP (n = 39)

HFP-T0 vs HFP-T6 P values

Responders (n = 21)

HFP-T0 vs HFP-T6 (R) P values

Non-Responders (n = 18)

HFP-T0 vs HFP-T6 (NR) P values

R vs NR (HFP-T0) P values

R vs NR (HFP-T6) P values

HFP-T0

HFP-T6

HFP-T0

HFP-T6

HFP-T0

HFP-T6

According to response to CRT

WBC

103/ µl

8.36 ± 1.71

8.34 ± 1.76

0.726

8.10 ± 1.58

8.10 ± 1.50

0.672

8.66 ± 1.84

8.64 ± 2.06

0.842

0.242

0.220

T cells

%

77.39 ± 9.95

77.07 ± 10.73

0.633

73.53 ± 11.44

73.33 ± 10.97

0.225

81.47 ± 6.04

81.99 ± 8.38

0.433

0.026

0.015

Cells/µl

1467.14 ± 638.21

1481.90 ± 588.58

0.326

1412.74 ± 573.74

1470.27 ± 611.70

0.768

1524.56 ± 712.17

1497.15 ± 576.25

0.404

0.518

0.892

Th cells

%

63.63 ± 10.85

61.99 ± 12.91

0.736

65.71 ± 10.77

62.76 ± 12.50

0.523

61.43 ± 10.78

61.02 ± 13.75

0.900

0.159

0.404

Cells/µl

919.55 ± 426.25

918.63 ± 383.68

0.589

900.76 ± 324.14

930.13 ± 389.04

1.000

939.37 ± 522.19

904.26 ± 389.07

0.495

0.940

0.718

Tc cells

%

31.33 ± 10.84

33.67 ± 12.27

0.270

29.92 ± 10.21

33.11 ± 12.54

0.580

32.82 ± 11.57

34.37 ± 12.28

0.501

0.391

0.560

Cells/µl

474.22 ± 274.04

519.76 ± 293.35

0.191

449.96 ± 284.46

515.26 ± 301.82

0.832

499.83 ± 268.33

525.40 ± 292.15

0.211

0.425

0.888

  1. Bold: Statistically significant differences (P < 0.05)
  2. Results are expressed as mean ± standard deviation
  3. Statistically significant differences were considered when P < 0.05 (Mann–Whitney U test and Wilcoxon signed-rank)
  4. Th T helper (CD4+) cells, Tc T cytotoxic (CD8+) cells, HFP heart failure patients, HFP-T0 (T0) baseline assessment, HFP-T6 (T6) follow-up evaluation, 6 months after Cardiac Resynchronization Therapy (CRT), R responders, NR non-responders, WBC white blood cells