BMC Cardiovascular Disorders

Table 2 Meta-analysis of the relationship between SNP rs918592 and the risk of ischemic stroke

From: PDE4D single nucleotide polymorphism rs918592 is associated with ischemic Stroke risk in Chinese populations: a meta-analysis

	All studies					Studies without Song’s (2015) study
	Pooled OR (95% CI)	P_OR	I²	P_H	Statistical model	Pooled OR (95% CI)	P_OR	I²	P_H	Statistical model
AG vs AA	0.78 (0.67–0.90)	0.001	27.3%	0.193	Fixed	0.72 (0.62–0.84)	< 0.001	0.0%	0.758	Fixed
GG vs AA	0.70 (0.54–0.91)	0.008	55.5%	0.017	Random	0.65 (0.51–0.83)	0.001	43.1%	0.080	Random
Dominant	0.74 (0.61–0.90)	0.003	48.8%	0.040	Random	0.71 (0.61–0.81)	< 0.001	11.9%	0.335	Fixed
Additive	0.83 (0.74–0.95)	0.005	52.5%	0.026	Random	0.81 (0.74–0.89)	< 0.001	37.5%	0.119	Fixed
Recessive	0.84 (0.74–0.96)	0.010	21.5%	0.245	Fixed	0.82 (0.71–0.94)	0.005	21.3%	0.254	Fixed

P_OR and P_H are P values for odds ratio and heterogeneity, respectively
P_OR values significant at P < 0.05 and P_H values significant at P < 0.10 are shown in bold

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ISSN: 1471-2261

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