Fig. 2
From: M1 macrophage-derived exosomes inhibit cardiomyocyte proliferation through delivering miR-155
Inhibition of cardiomyocyte proliferation by M1-Exos A) After PKH26-labeled exosomes (red) were added to cardiomyocytes at a concentration of 2 × 109/mL for 10 h, the uptake of exosome was observed by confocal laser microscopy. Scale bar: 100 μm. B) M0-Exos and M1-Exos were added to cardiomyocytes at a concentration of 2 × 109/mL for 24 h, and the number of cardiomyocytes labeled with pH3 or ki67 (red) was observed by immunocytochemistry. Scale bar: 400 μm. Each experiment in this figure was replicated more than three times. *P < 0.05, ***P < 0.001, M1-Exos group compared with M0-Exos group