Fig. 3
From: M1 macrophage-derived exosomes inhibit cardiomyocyte proliferation through delivering miR-155
Delivery of miR-155 to Cardiomyocytes through M1-Exos A) M1 macrophages were treated with 50 ng/mL GM-CSF and 20 ng/mL IFN-γ for 24 h. The expression of miR-155 in cells (left) and exosome (right) was detected by qRT-PCR. B) After M0-Exos and M1-Exos were added to cardiomyocytes at a concentration of 2 × 109/mL for 24 h, the expression of miR-155 in cardiomyocytes was detected by qRT-PCR. Each experiment in this figure was replicated more than three times. ***P < 0.001, M1 vs. M0, or M1-Exos vs. M0-Exos treatment