Fig. 7
From: M1 macrophage-derived exosomes inhibit cardiomyocyte proliferation through delivering miR-155
Working mode diagram When macrophages differentiated into M1 macrophages which secrete M1-Exos in large amount. M1-Exos carried miR-155 into cardiomyocytes and targeted IL-6R, thus inhibiting the IL-6R/JAK/STAT pathway, which resulted in the inhibition of cardiomyocyte proliferation