Fig. 4
From: β-catenin mediates monocrotaline-induced pulmonary hypertension via glycolysis in rats
Inhibition of β-catenin suppresses PASMC proliferation and migration in vitro. A PASMC proliferation was assessed using the EdU assay. Scale bar = 50 μm. B Cell migration were assessed by wound healing and Transwell assays. Scale bar = 200 μm. C-F Bars represent the proliferation of PASMCs as assessed by EdU, CCK-8, wound healing and Transwell assays. The following comparisons were made: control vs. LPS, LPS vs. LPS + XAV939, LPS vs. LPS + LiCl, and LPS + XAV939 vs. LPS + XAV939 + FBP. The data are presented as the means ± SDs; ns P ≥ 0.05, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001; n = 3/group