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Table 1 Baseline characteristics in persistent AF patients with CHAD2DS2-VASc scores ≤ 2 and ≥ 3

From: Left atrial remodeling and voltage-guided ablation outcome in persistent atrial fibrillation patients according to CHA2DS2-VASc score

 

CHAD2DS2-VASc score ≤ 2 (n = 80)

CHAD2DS2-VASc score ≥ 3 (n = 58)

P value

Age, years

62 (56.75-67)

70 (65–74)

< 0.01

Female sex, n (%)

13 (16.25%)

28 (48.28%)

< 0.01

CHA2DS2-VASc score, n

1.26 (0.72)

3.78 (0.9)

< 0.01

HAS BLED score, n

0.81 (0.71)

1.9 (0.83)

< 0.01

BMI, kg/m²

29.1 (26.9–32)

30.4 (25.9–32.9)

0.45

Hypertension, n (%)

35 (43.75%)

51 (87.93%)

< 0.01

Diabetes mellitus, n (%)

4 (5%)

22 (37.93%)

< 0.01

Dyslipidemia, n (%)

22 (27.5%)

28 (48.28%)

0.02

OSA, n (%)

23 (28.75%)

19 (32.76%)

0.75

eGFR, ml/min/1,73²

89 (74.75-95)

71 (60-89.5)

< 0.01

Coronary artery disease, n (%)

10 (12.5%)

5 (8.62%)

0.66

Time to treatment, days

702 (197–1531)

620 (240–1848)

0.96

Reported AF duration, months

  

0.09

< 3 months

62 (78.48%)

79.31% (46)

 

≥ 3 to < 6 months

11 (13.92%)

4 (6.9%)

 

≥ 6 to < 9 months

2 (2.53%)

7 (12.07%)

 

≥ 9 to < 12 months

2 (2.53%)

0 (0%)

 

≥ 12 months

2 (2.53%)

1 (1.72%)

 

Thromboembolism, n (%)

2 (2.5%)

14 (24.14%)

< 0.01

P-wave duration ≥ 150 ms, n (%)

24 (30%)

31 (54.39%)

< 0.01

LVEF, % before ablation

61 (51–67)

58 (47-64.25)

0.26

Per-procedural LAIV excluding LAA, ml

132.5 (110-151.3)

130 (117.5–150)

0.87

Per-procedural LAIVI excluding LAA, ml.m2

62.6 (53.2–68.6)

64.8 (56–74)

0.13

Beta-blocker

65 (81.25%)

50 (86.21%)

0.59

ACEi/ARB

45 (56.25%)

41 (70.69%)

0.12

Aldosterone receptor antagonist

12 (15%)

17 (29.31%)

0.07

  1. Data are presented as a value (with percentage) for categorical variables, median (25th − 75th percentile) or mean ± SD for quantitative variables. A two-tailed p value of < 0.05 was considered significant
  2. Time to treatment = time from first clinical diagnosis of AF to ablation procedure
  3. Abbreviations:
  4. AF = atrial fibrillation; BMI = body mass index; OSA = obstructive sleep apnea; eGFR = estimated glomerular filtration rate; LVEF = left ventricle ejection fraction; LAIV = left atrial intracavitary volume; LAIVI = left atrial intracavitary volume index; LAA = left atrial appendage; ACEi/ARB = angiotensin-convertinge enzyme inhibitor/Angiotensin II receptor blocker