Fig. 5
From: Effect of NLRP3 gene knockdown on pyroptosis and ferroptosis in diabetic cardiomyopathy injury
NLRP3 knockdown inhibits HG-induced NLRP3 inflammasome related pyroptosis in H9C2 cardiac cells. The protein levels of NLRP3 (A), ASC (B), Cleaved-caspase-1 (C), GSDMD-NT (D), IL-1β (E) and IL-18 (F) in H9C2 cardiac cells normalized by GAPDH levels. (G) Representative blots in H9C2 cardiac cells. (mean ± SD, n = 3). *P < 0.05, **P < 0.01 vs. CON; #P < 0.05, ##P < 0.01 vs. HG