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Fig. 1 | BMC Cardiovascular Disorders

Fig. 1

From: Nitrogen-containing bisphosphonate induces enhancement of OPG expression and inhibition of RANKL expression via inhibition of farnesyl pyrophosphate synthase to inhibit the osteogenic differentiation and calcification in vascular smooth muscle cells

Fig. 1

Schematic diagram of the mevalonate pathway. FPPS, farnesyl pyrophosphate synthase; SQS, squalene synthase; FNT, farnesyltransferase; GGT-1, geranylgeranyltransferase-1; GGPPS, geranylgeranyl pyrophosphate synthase; N-BPs, nitrogen-containing bisphosphonatesand; FOH, farnesol; GGOH, geranylgeraniol

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BMC Cardiovascular Disorders

ISSN: 1471-2261

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