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Table 2 Logistic regression of risk factors for AKI-KRT

From: Assessing the predictive value of elevated postoperative syndecan-1 levels for progressive acute kidney injury and kidney replacement therapy necessity in adult cardiac surgery patients

 

Univariate analysis

 

Multivariate analysis

 

OR

95%CI

p value

 

OR

95%CI

p value

Gender

4.49

0.56  35.81

0.156

    

Age

0.98

0.94  1.02

0.281

    

Hypertension

2.04

0.65  6.36

0.220

    

Diabetes Mellitus

0.41

0.05  3.31

0.400

    

EUROScore II

1.50

1.19  1.88

< 0.001

 

1.76

1.13  2.73

0.012

Baseline laboratory indices

       

 Hemoglobin (g/L)

1.03

1.00  1.05

0.059

    

 eGFR (mL/min/1.73m2)

0.99

0.96  1.01

0.322

    

 Albumin (g/L)

1.05

0.92  1.20

0.446

    

Surgery type

       

 CABG

 

1.00 (Reference)

     

 Valve

0.97

0.11–8.94

0.981

    

 Valve & CABG

4.49

0.56–35.81

0.996

    

CPB duration

1.02

1.01  1.03

< 0.001

 

1.01

0.99  1.02

0.265

Aortic clamping time

1.03

1.01  1.05

0.002

 

1.02

0.99  1.05

0.125

Postoperative indices

       

 APACHE II Score

1.33

1.17  1.50

< 0.001

 

1.36

1.07  1.72

0.011

 Serum SDC1

1.010

1.005  1.014

< 0.001

 

1.011

1.003  1.020

0.008

 IL6

1.00

1.00  1.01

0.125

    

 IL8

1.01

1.01  1.02

0.006

 

1.01

0.99  1.03

0.215

 TNFa

0.95

0.84  1.07

0.375

    

 PCT

1.01

0.99  1.03

0.181

    
  1. AKI: Acute kidney injury; APACHE: Acute Physiology, Age, Chronic Health Evaluation; CABG: Coronary artery bypass grafting; CPB: Cardiopulmonary bypass; eGFR: Estimated glomerular filtration rate, calculated by CKD-EPI formulae; KRT: kidney replacement therapy; LVEF: Left ventricular ejection fraction; PCT: Procalcitonin; TNF: Tumor necrosis factor