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Table 1 Clinical characteristics of the study population

From: Presence of coronary artery disease in adults with newly detected diabetes mellitus

 

Non-DM (n = 338)

Newly detected DM (n = 54)

Known DM (n = 52)

p-value (Non-DM vs. Newly detected DM)

p-value (Non-DM vs. Known DM)

p-value (Newly detected DM vs. Known DM)

p-value (3 Groups)

Age (years)

55.2 ± 9.3

58.6 ± 7.5

60.9 ± 7.7

0.0112

< 0.0001

0.1098

< 0.0001

Male (n, %)

244 (72.2)

42 (77.8)

43 (82.7)

0.3906

0.1097

0.5257

0.2205

Hypertension (n, %)

128 (37.9)

18 (33.3)

33 (63.5)

0.522

< 0.0001

0.0019

0.0012

Chronic kidney disease (n, %)

16 (4.7)

2 (3.7)

6 (11.5)

0.7299

0.0736

0.1269

0.1092

Ever-smoker (n, %)

92 (27.2)

22 (40.7)

27 (51.9)

0.0422

0.0003

0.2483

0.0006

Ever-alcohol user (n, %)

84 (25.2)

19 (35.2)

17 (34.0)

0.1213

0.185

0.899

0.1661

Body mass index (kg/m2)

25.6 ± 3.7

27.4 ± 4.3

25.8 ± 3.8

0.0009

0.6876

0.0411

0.0038

Waist circumference (cm)

88.0 ± 9.8

93.5 ± 11.4

91.4 ± 10.2

0.0002

0.0234

0.3174

0.0003

Large waist circumference a (n, %)

173 (51.2)

35 (64.8)

31 (59.6)

0.0624

0.2571

0.5809

0.118

Systolic blood pressure (mmHg)

126.8 ± 17.6

128.9 ± 16.2

131.7 ± 14.1

0.4077

0.0595

0.3585

0.1384

Diastolic blood pressure (mmHg)

78.9 ± 10.9

78.7 ± 10.8

79.7 ± 11.2

0.8987

0.6219

0.6374

0.8682

Fasting plasma glucose (mmol/L)

5.5 ± 0.5

7.3 ± 1.9

7.7 ± 2.1

< 0.0001

< 0.0001

0.3071

< 0.0001

Hemoglobin A1c (%)

5.6 ± 0.3

7.0 ± 1.1

7.2 ± 1.1

< 0.0001

< 0.0001

0.429

< 0.0001

Total cholesterol (mmol/L)

5.2 ± 1.0

5.4 ± 1.1

4.5 ± 1.0

0.3487

< 0.0001

0.0001

< 0.0001

Triglyceride (mmol/L)

1.7 ± 1.1

2.3 ± 1.6

1.8 ± 1.0

0.0011

0.4829

0.0751

0.0038

High level of triglyceride b (n, %)

117 (34.6)

29 (53.7)

21 (40.4)

0.0071

0.418

0.1697

0.0244

High-density lipoprotein (mmol/L)

1.3 ± 0.4

1.2 ± 0.4

1.1 ± 0.3

0.0778

0.002

0.2336

0.0029

Low level of high-density lipoprotein c (n, %)

103 (30.5)

23 (42.6)

24 (46.2)

0.0766

0.0247

0.7122

0.0289

Low-density lipoprotein (mmol/L)

3.3 ± 0.9

3.5 ± 1.0

2.8 ± 0.9

0.1955

0.0002

0.0002

0.0002

High level of low-density lipoprotein d (n, %)

167 (49.4)

28 (51.9)

14 (26.9)

0.7388

0.0025

0.0087

0.0078

Estimated glomerular filtration rate (mL/min)

86.4 ± 18.5

90.4 ± 16.7

84.0 ± 21.6

0.1379

0.4063

0.0934

0.2014

  1. DM: diabetes mellitus. Values are mean ± standard deviation for continuous variables, and n (%) for binary variables. a Large waist circumference was defined as waist circumference ≥ 90 cm in men and ≥ 80 cm in women. b High level of triglyceride was defined as triglyceride ≥ 1.7 mmol/L (150 mg/dL). c Low level of high-density lipoprotein was defined as high-density lipoprotein < 1.03 mmol/L (40 mg/dL) in men and < 1.29 mmol/L (50 mg/dL) in women. d High level of low-density lipoprotein was defined as low-density lipoprotein ≥ 3.36 mmol/L (130 mg/dL)
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BMC Cardiovascular Disorders

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