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Table 2 Baseline characteristics between survivors and non-survivors at 365 days

From: Association of elevated albumin-corrected anion gap with all-cause mortality risk in atrial fibrillation: a retrospective study

Variables

Total (N = 2920)

survivors (N = 1775)

non-survivors (N = 1145)

P-value

ACAG, mmol/L

19.25 (16.75, 22.50)

18.50 (16.25, 21.25)

20.50 (17.75, 24.25)

< 0.01

Paroxysmal atrial fibrillation, n (%)

47 (1.61)

33 (1.86)

14 (1.22)

0.182

Demographic variables

    

 Age (years)

78.00 (69.00, 86.00)

75.00 (66.00, 83.00)

82.00 (74.00, 88.00)

< 0.01

 Sex, male, n (%)

1604 (54.93)

1012 (57.01)

592 (51.70)

< 0.01

 Race, White, n (%)

2046 (70.07)

1246 (70.20)

800 (69.87)

0.85

Comorbidities, n (%)

    

 Myocardial infarction

747 (25.58)

415 (23.38)

332 (29.00)

< 0.01

 Congestive heart failure

1500 (51.37)

851 (47.94)

649 (56.68)

< 0.01

 Diabetes

969 (33.18)

562 (31.66)

407 (35.55)

0.03

 Hypertension

1154 (39.52)

716 (40.34)

438 (38.25)

0.26

 Obesity

341 (11.68)

240 (13.52)

101 (8.82)

< 0.01

 Peripheral vascular disease

446 (15.27)

242 (13.63)

204 (17.82)

< 0.01

 Cerebrovascular disease

725 (24.83)

398 (22.42)

327 (28.56)

< 0.01

 COPD

866 (29.66)

518 (29.18)

348 (30.39)

0.48

 Rheumatic Disease

138 (4.73)

78 (4.39)

60 (5.24)

0.29

 Paraplegia

298 (10.21)

162 (9.13)

136 (11.88)

0.02

 Renal Disease

805 (27.57)

417 (23.49)

388 (33.89)

< 0.01

 Liver Disease

178 (6.10)

84 (4.73)

94 (8.21)

< 0.01

Laboratory data

    

 Hematocrit, %

35.80 (31.60, 40.50)

36.20 (32.00, 40.80)

35.30 (30.90, 40.00)

< 0.01

 Hemoglobin, g/dL

11.70 (10.20, 13.30)

11.90 (10.40, 13.50)

11.40 (9.90, 12.80)

< 0.01

 Platelets, K/uL

211.00 (161.00, 279.00)

210.00 (162.00, 273.00)

213.00 (159.00, 288.00)

0.42

 WBC, K/uL

12.90 (9.30, 18.00)

12.40 (9.10, 17.10)

13.70 (9.70, 19.20)

< 0.01

 RDW, %

14.60 (13.70, 16.00)

14.30 (13.50, 15.50)

15.10 (14.00, 16.70)

< 0.01

 Albumin, g/dL

3.40 (2.90, 3.80)

3.50 (3.00, 3.90)

3.30 (2.80, 3.70)

< 0.01

 AG, mmol/L

17.00 (14.00, 20.00)

16.00 (14.00, 19.00)

18.00 (15.00, 21.00)

< 0.01

 BUN, mg/dL

27.00 (19.00, 45.00)

24.00 (17.00, 37.50)

34.00 (23.00, 56.00)

< 0.01

 Calcium, mg/dL

8.60 (8.20, 9.10)

8.70 (8.20, 9.10)

8.60 (8.10, 9.10)

0.34

 Chloride, mEq/L

105.00 (102.00, 109.00)

106.00 (102.00, 109.00)

105.00 (101.00, 110.00)

0.72

 Creatinine, mg/dL

1.30 (0.90, 1.90)

1.20 (0.90, 1.70)

1.50 (1.00, 2.30)

< 0.01

 Glucose, g/dL

152.00 (121.00, 208.00)

147.00 (118.00, 194.00)

165.00 (126.00, 226.00)

< 0.01

 Sodium, mEq/L

140.00 (138.00, 143.00)

140.00 (138.00, 143.00)

141.00 (138.00, 144.00)

< 0.01

 Potassium, mEq/L

4.50 (4.10, 5.00)

4.40 (4.10, 4.90)

4.60 (4.20, 5.30)

< 0.01

 INR

1.40 (1.20, 2.10)

1.40 (1.20, 1.90)

1.50 (1.20, 2.40)

< 0.01

 prothrombin time, s

15.70 (13.30, 22.40)

15.30 (13.10, 20.30)

16.60 (13.70, 25.90)

< 0.01

 partial thromboplastin time, s

35.40 (29.60, 54.52)

34.60 (29.50, 53.10)

37.00 (29.80, 57.20)

0.02

Vital signs

    

 Heart rate, beats/min

85.00 (73.00, 98.00)

84.00 (72.50, 98.00)

86.00 (74.00, 99.00)

0.05

 Systolic blood pressure, mmHg

115.00 (106.00, 128.00)

117.00 (107.00, 129.00)

113.00 (104.00, 126.00)

< 0.01

 Diastolic blood pressure, mmHg

62.00 (55.00, 69.00)

63.00 (56.00, 71.00)

60.00 (54.00, 68.00)

< 0.01

 Mean blood pressure, mmHg

77.00 (71.00, 85.00)

78.00 (72.00, 86.00)

75.00 (69.00, 83.00)

< 0.01

Clinical severity

    

 SOFA

5.00 (3.00, 8.00)

4.00 (2.00, 7.00)

6.00 (4.00, 9.00)

< 0.01

 OASIS

34.00 (29.00, 40.00)

33.00 (27.00, 38.00)

37.00 (32.00, 44.00)

< 0.01

 SAPS II

39.00 (32.00, 49.00)

36.00 (30.00, 44.00)

45.00 (37.00, 54.00)

< 0.01

Diagnostic and therapeutic n (%)

    

 Aspirin

1246 (42.67)

759 (42.76)

487 (42.53)

0.90

 Clopidogrel

218 (7.47)

121 (6.82)

97 (8.47)

0.10

 Statin

1220 (41.78)

783 (44.11)

437 (38.17)

< 0.01

 Beta-Blockers

1896 (64.93)

1191 (67.10)

705 (61.57)

< 0.01

 ACEI/ARB

286 (9.79)

194 (10.93)

92 (8.03)

0.01

 Amiodarone

720 (24.66)

428 (24.11)

292 (25.50)

0.40

 Dabigatran

26 (0.89)

20 (1.13)

6 (0.52)

0.09

 Heparin

2263 (77.50)

1351 (76.11)

912 (79.65)

0.03

 Warfarin

568 (19.45)

389 (21.92)

179 (15.63)

< 0.01

 Vasoactive drug

2203 (75.45)

1317 (74.20)

886 (77.38)

0.05

 Intra-aortic balloon pump

23 (0.79)

17 (0.96)

6 (0.52)

0.196

 Coronary angiography

48 (1.64)

33 (1.86)

15 (1.31)

0.255

  1. Abbreviation: ACAG, albumin-corrected anion gap; COPD, chronic pulmonary disease; WBC, white blood cell; RDW, red cell distribution width; AG, anion gap; BUN, blood urea nitrogen; INR, international normalized ratio; SOFA, sequential organ failure assessment; OASIS, Oxford Acute Severity of Illness Score; SAPS II, simplified acute physiology score; ACEI/ARB, angiotensin-converting enzyme inhibitor/ angiotensin II receptor blocker