Variables | Total (N = 2920) | survivors (N = 1775) | non-survivors (N = 1145) | P-value |
---|---|---|---|---|
ACAG, mmol/L | 19.25 (16.75, 22.50) | 18.50 (16.25, 21.25) | 20.50 (17.75, 24.25) | < 0.01 |
Paroxysmal atrial fibrillation, n (%) | 47 (1.61) | 33 (1.86) | 14 (1.22) | 0.182 |
Demographic variables | Â | Â | Â | Â |
 Age (years) | 78.00 (69.00, 86.00) | 75.00 (66.00, 83.00) | 82.00 (74.00, 88.00) | < 0.01 |
 Sex, male, n (%) | 1604 (54.93) | 1012 (57.01) | 592 (51.70) | < 0.01 |
 Race, White, n (%) | 2046 (70.07) | 1246 (70.20) | 800 (69.87) | 0.85 |
Comorbidities, n (%) | Â | Â | Â | Â |
 Myocardial infarction | 747 (25.58) | 415 (23.38) | 332 (29.00) | < 0.01 |
 Congestive heart failure | 1500 (51.37) | 851 (47.94) | 649 (56.68) | < 0.01 |
 Diabetes | 969 (33.18) | 562 (31.66) | 407 (35.55) | 0.03 |
 Hypertension | 1154 (39.52) | 716 (40.34) | 438 (38.25) | 0.26 |
 Obesity | 341 (11.68) | 240 (13.52) | 101 (8.82) | < 0.01 |
 Peripheral vascular disease | 446 (15.27) | 242 (13.63) | 204 (17.82) | < 0.01 |
 Cerebrovascular disease | 725 (24.83) | 398 (22.42) | 327 (28.56) | < 0.01 |
 COPD | 866 (29.66) | 518 (29.18) | 348 (30.39) | 0.48 |
 Rheumatic Disease | 138 (4.73) | 78 (4.39) | 60 (5.24) | 0.29 |
 Paraplegia | 298 (10.21) | 162 (9.13) | 136 (11.88) | 0.02 |
 Renal Disease | 805 (27.57) | 417 (23.49) | 388 (33.89) | < 0.01 |
 Liver Disease | 178 (6.10) | 84 (4.73) | 94 (8.21) | < 0.01 |
Laboratory data | Â | Â | Â | Â |
 Hematocrit, % | 35.80 (31.60, 40.50) | 36.20 (32.00, 40.80) | 35.30 (30.90, 40.00) | < 0.01 |
 Hemoglobin, g/dL | 11.70 (10.20, 13.30) | 11.90 (10.40, 13.50) | 11.40 (9.90, 12.80) | < 0.01 |
 Platelets, K/uL | 211.00 (161.00, 279.00) | 210.00 (162.00, 273.00) | 213.00 (159.00, 288.00) | 0.42 |
 WBC, K/uL | 12.90 (9.30, 18.00) | 12.40 (9.10, 17.10) | 13.70 (9.70, 19.20) | < 0.01 |
 RDW, % | 14.60 (13.70, 16.00) | 14.30 (13.50, 15.50) | 15.10 (14.00, 16.70) | < 0.01 |
 Albumin, g/dL | 3.40 (2.90, 3.80) | 3.50 (3.00, 3.90) | 3.30 (2.80, 3.70) | < 0.01 |
 AG, mmol/L | 17.00 (14.00, 20.00) | 16.00 (14.00, 19.00) | 18.00 (15.00, 21.00) | < 0.01 |
 BUN, mg/dL | 27.00 (19.00, 45.00) | 24.00 (17.00, 37.50) | 34.00 (23.00, 56.00) | < 0.01 |
 Calcium, mg/dL | 8.60 (8.20, 9.10) | 8.70 (8.20, 9.10) | 8.60 (8.10, 9.10) | 0.34 |
 Chloride, mEq/L | 105.00 (102.00, 109.00) | 106.00 (102.00, 109.00) | 105.00 (101.00, 110.00) | 0.72 |
 Creatinine, mg/dL | 1.30 (0.90, 1.90) | 1.20 (0.90, 1.70) | 1.50 (1.00, 2.30) | < 0.01 |
 Glucose, g/dL | 152.00 (121.00, 208.00) | 147.00 (118.00, 194.00) | 165.00 (126.00, 226.00) | < 0.01 |
 Sodium, mEq/L | 140.00 (138.00, 143.00) | 140.00 (138.00, 143.00) | 141.00 (138.00, 144.00) | < 0.01 |
 Potassium, mEq/L | 4.50 (4.10, 5.00) | 4.40 (4.10, 4.90) | 4.60 (4.20, 5.30) | < 0.01 |
 INR | 1.40 (1.20, 2.10) | 1.40 (1.20, 1.90) | 1.50 (1.20, 2.40) | < 0.01 |
 prothrombin time, s | 15.70 (13.30, 22.40) | 15.30 (13.10, 20.30) | 16.60 (13.70, 25.90) | < 0.01 |
 partial thromboplastin time, s | 35.40 (29.60, 54.52) | 34.60 (29.50, 53.10) | 37.00 (29.80, 57.20) | 0.02 |
Vital signs | Â | Â | Â | Â |
 Heart rate, beats/min | 85.00 (73.00, 98.00) | 84.00 (72.50, 98.00) | 86.00 (74.00, 99.00) | 0.05 |
 Systolic blood pressure, mmHg | 115.00 (106.00, 128.00) | 117.00 (107.00, 129.00) | 113.00 (104.00, 126.00) | < 0.01 |
 Diastolic blood pressure, mmHg | 62.00 (55.00, 69.00) | 63.00 (56.00, 71.00) | 60.00 (54.00, 68.00) | < 0.01 |
 Mean blood pressure, mmHg | 77.00 (71.00, 85.00) | 78.00 (72.00, 86.00) | 75.00 (69.00, 83.00) | < 0.01 |
Clinical severity | Â | Â | Â | Â |
 SOFA | 5.00 (3.00, 8.00) | 4.00 (2.00, 7.00) | 6.00 (4.00, 9.00) | < 0.01 |
 OASIS | 34.00 (29.00, 40.00) | 33.00 (27.00, 38.00) | 37.00 (32.00, 44.00) | < 0.01 |
 SAPS II | 39.00 (32.00, 49.00) | 36.00 (30.00, 44.00) | 45.00 (37.00, 54.00) | < 0.01 |
Diagnostic and therapeutic n (%) | Â | Â | Â | Â |
 Aspirin | 1246 (42.67) | 759 (42.76) | 487 (42.53) | 0.90 |
 Clopidogrel | 218 (7.47) | 121 (6.82) | 97 (8.47) | 0.10 |
 Statin | 1220 (41.78) | 783 (44.11) | 437 (38.17) | < 0.01 |
 Beta-Blockers | 1896 (64.93) | 1191 (67.10) | 705 (61.57) | < 0.01 |
 ACEI/ARB | 286 (9.79) | 194 (10.93) | 92 (8.03) | 0.01 |
 Amiodarone | 720 (24.66) | 428 (24.11) | 292 (25.50) | 0.40 |
 Dabigatran | 26 (0.89) | 20 (1.13) | 6 (0.52) | 0.09 |
 Heparin | 2263 (77.50) | 1351 (76.11) | 912 (79.65) | 0.03 |
 Warfarin | 568 (19.45) | 389 (21.92) | 179 (15.63) | < 0.01 |
 Vasoactive drug | 2203 (75.45) | 1317 (74.20) | 886 (77.38) | 0.05 |
 Intra-aortic balloon pump | 23 (0.79) | 17 (0.96) | 6 (0.52) | 0.196 |
 Coronary angiography | 48 (1.64) | 33 (1.86) | 15 (1.31) | 0.255 |