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Table 2 Negative binomial regression for the correlation of echocardiographic cardiac parameters with global cognitive score of MoCA

From: Association between echocardiographic parameters of cardiac structure and function and mild cognitive impairment

Cardiac variables

30—global cognitive score

Beta (SE)

p-value

adj. Beta (SE)*

adj. p-value*

LV diastolic dysfunction

0.244 (0.045)

< 0.001

0.234 (0.045)

< 0.001

LA enlargement

−0.055 (0.045)

0.221

−0.052 (0.046)

0.264

Biatrial enlargement

0.090 (0.094)

0.341

0.066 (0.095)

0.489

IVST, per 1 mm

0.028 (0.016)

0.079

0.034 (0.016)

0.036

LV mass index, per 10 g/m2

0.007 (0.013)

0.567

0.005 (0.014)

0.688

LV hypertrophy

−0.011 (0.100)

0.911

−0.080 (0.101)

0.426

Aortic sinus diameter, per 1 mm

−0.001 (0.006)

0.806

−0.001 (0.006)

0.839

Aortic regurgitation

0.032 (0.048)

0.506

0.020 (0.049)

0.682

LV ejection fraction, per 1%

−0.004 (0.003)

0.208

−0.002 (0.003)

0.512

E/A, per 0.1 unit

0.009 (0.006)

0.153

0.005 (0.006)

0.408

  1. *Negative binomial regression was adjusted for age, sex, education, hypertension, atrial fibrillation, coronary artery disease, chronic heart failure, stroke, chronic kidney disease, diabetes mellitus, hyperlipidemia, smoking, systolic blood pressure, diastolic blood pressure, estimated glomerular filtration rate, fasting plasma glucose, total cholesterol, low-density lipoprotein cholesterol, and body mass index
  2. SE standard error, LV left ventricular, LA left atrial, IVST interventricular septal thickness, E/A ratio of the early diastolic transmitral flow velocity and late atrial diastolic transmitral flow velocity