Table 3 Details of procedural treatments in intervention and control arms during the index hospitalization
RCT Name | Intervention Arm (Invasive strategy) | Control Arm (Conservative strategy) | Follow-up Duration | ||
|---|---|---|---|---|---|
| Â | Coronary angiography | Coronary revascularization (PCI/CABG) | Coronary angiography | Coronary revascularization (PCI/CABG) | Â |
TACTICS–TIMI 18 [9] |  +  (95% of the patients randomized to this arm underwent coronary angiography; the time interval between randomization and coronary angiography has not been determined |  ±  (61% of the patients randomized to this arm) |  ±  (49% of the patients randomized to this arm underwent coronary angiography; the time interval between randomization and coronary angiography has not been determined) |  ±  (32% of the patients randomized to this arm) | 6 months |
FIR Trials [27] | Not Specified | Not Specified | Not Specified | Not Specified | 5 years |
Italian Elderly ACS [31] |  +  (88% of the patients randomized to this arm underwent coronary angiography with a median of 24 h interval from the time of randomization) |  ±  (56% of the patients randomized to this arm) |  ±  (29% of the patients randomized to this arm underwent coronary angiography with a median of 67 h interval from the time of randomization) |  ±  (23% of the patients randomized to this arm) | 1 year |
MOSCA [30] |  +  (100% of the patients randomized to this arm underwent coronary angiography; the time interval between randomization and coronary angiography has not been determined) |  ±  (58% of the patients randomized to this arm) |  ±  (20% of the patients randomized to this arm underwent coronary angiography; the time interval between randomization and coronary angiography has not been determined) |  ±  (9% of the patients randomized to this arm) | Median follow-up of 1.9 years |
After Eighty |  +  (96% of the patients randomized to this arm underwent coronary angiography with a mean of 3 days interval from the time of randomization) |  ±  (50% of the patients randomized to this arm) |  ±  (None of the patients randomized to this arm underwent coronary angiography) |  ±  (None of the patients randomized to this arm underwent revascularization) | Median follow-up of 5.3 years |
80 + study [29] |  +  (96% of the patients randomized to this arm underwent coronary angiography; the time interval between randomization and coronary angiography has not been determined) |  ±  (62% of the patients randomized to this arm) |  ±  (4% of patients randomized to this arm underwent coronary angiography; the time interval between randomization and coronary angiography has not been determined) |  ±  (4% of the patients randomized to this arm underwent revascularization) | 1 year |
RINCAL [28] |  +  (92% of the patients randomized to this arm underwent coronary angiography with a mean of 2 days interval from the time of randomization) |  ±  (51% of the patients randomized to this arm) |  ±  (9% of patients randomized to this arm underwent coronary angiography; the time interval between randomization and coronary angiography has not been determined) |  ±  (3% of the patients randomized to this arm underwent revascularization) | Median follow-up of 1 year |
MOSCA-FRAIL |  +  (98% of the patients randomized to this arm underwent coronary angiography; the time interval between randomization and coronary angiography has not been determined) |  ±  (60% of the patients randomized to this arm) |  ±  (11% of patients randomized to this arm underwent coronary angiography; the time interval between randomization and coronary angiography has not been determined) |  ±  (10% of the patients randomized to this arm underwent revascularization) | Median follow-up of 3 years |
SENIOR-RITA [26] |  +  (90% of the patients randomized to this arm underwent coronary angiography with a median of 3 days intervals from the time of randomization) |  ±  (50% of the patients randomized to this arm) |  ±  (6% of patients randomized to this arm underwent coronary angiography within 7 days of randomization) |  ±  (The proportion of patients randomized to this arm and underwent revascularization has not been determined) | Median follow-up of 4.1 years |