Fig. 3
From: Amiodarone use and prolonged mechanical ventilation after cardiac surgery: a single-center analysis
Treatment effect on delayed extubation by subgroup, showed that amiodarone was a risk factor for delayed extubation for all surgical types, after adjusting for confounding variables (hypertension, stroke, amiodarone, age, LVEF, CPB, DHCA and plasma). Subgroup analysis revealed that Isolated CABG (OR: 2.42, 95%CI: 1.01–5.82, P = 0.047), AVR or MVR (OR: 2.13, 95%CI: 1.33–3.42, P = 0.002), and Others (OR: 4.44, 95%CI: 1.26–15.6, P = 0.020), suggesting that amiodarone were identified as risk factors for delayed extubation in these three surgical categories. In the case of AVR + MVR (OR: 0.63, 95%CI: 0.25–1.59, P = 0.333), Valvular surgery + CABG (OR: 0.64, 95%CI: 0.16–2.59, P = 0.532), and thoracic aortic surgery (OR: 1.54, 95%CI: 0.72–3.29, P = 0.260), no statistically significant associations were identified