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Table 1 provides details of the characteristics included in this study

From: Effect of ABCG2 c.421 C> A (rs2231142) single nucleotide polymorphisms on the lipid-modulating efficacy of rosuvastatin: a meta-analysis

First author

Year

Country

Number of patients

treatment

dose/day

Gene sequencing methods

outcomes

NOS

CC

CA + AA

Bailey [13]

2010

United Kingdom

239

71

12 weeks

10 mg

PCR

â‘¢

7

Kim TE [14]

2017

Korea

14

4

8 weeks

20 mg

PCR

①②③④

4

Kim Y [12]

2019

Korea

10

9

3 weeks

20 mg

PCR

①②③④

4

Lee HK [15]

2013

China

129

147

 > 4 weeks

10 mg

PCR

â‘¢

5

Tomlinson [11]

2010

China

158

147

 > 4 weeks

10 mg

PCR

â‘¡â‘¢

7

Zhang [16]

2020

China

75

194

 > 4 weeks

10 mg

Sanger Dideoxy DNA sequencing

①③④

5

Ma [17]

2020

China

78

72

6 weeks

10 mg

PCR

①②③④

5

  1. â‘ TG: triglycerides
  2. â‘¡TC: total cholesterol
  3. â‘¢LDL-C: low-density lipoprotein cholesterol
  4. â‘£HDL-C: high-density lipoprotein cholesterol