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Table 1 Demographic and clinical characteristics of CAD-, CAD+

From: A-kinase anchoring protein 1: an independent predictor of coronary artery disease

Variable

CAD-

CAD+

P value

Male

46 (68.7%)

139 (73.9%)

0.4061

Age, yrs

63 (55, 69)

65 (56, 71)

0.5392

Smoking

13 (19.4%)

56 (29.8%)

0.1001

Hypertension

55 (82.1%)

148 (78.7%)

0.5571

Diabetes mellitus

13 (20.1%)

79 (42.0%)

< 0.011

Hyperlipidemia

25 (37.3%)

86 (45.7%)

0.2321

Body mass index, kg/m2

24.82 ± 3.61

25.03 ± 2.63

0.6623

Systolic blood pressure, mmHg

130 (121, 142)

133 (120, 145.5)

0.9072

Diastolic blood pressure, mmHg

80 (74, 90)

80 (72, 88)

0.3502

Alanine transaminase, U/L

19.00 (15.00, 31.00)

20.40 (14.00, 29.95)

0.9432

Creatinine, mg/dL

69.00 (57.00, 78.40)

69.40 (61.35, 79.85)

0.1982

Fasting blood-glucose, mmol/L

5.22 (4.75, 5.79)

5.19 (4.51, 6.57)

0.9182

Glycosylated hemoglobin, %

6.0 (5.7, 6.3)

6.3 (5.8, 7.3)

0.0042

Total cholesterol, mmol/L

4.20 (3.27, 4.96)

4.31 (3.64, 5.00)

0.1792

Triglyceride, mmol/L

1.46 (0.93, 1.81)

1.49 (1.07, 2.06)

0.4242

High-density lipoprotein, mmol/L

1.07 (0.96, 1.20)

0.95 (0.82, 1.17)

0.0022

Low-density lipoprotein, mmol/L

2.65 (2.03, 3.15)

2.50 (1.96, 3.28)

0.7552

C-reactive protein, mg/L

0.33 (0.21, 1.34)

1.43 (0.42, 5.17)

< 0.012

LVEF, %

68.00 (62.75,73.00)

62.00 (56.00,68.00)

< 0.012

AKAP1, ng/mL

0.62 (0.44,0.88)

0.42 (0.29,0.73)

< 0.012

Aspirin

18 (26.9%)

65 (34.6%)

0.2481

Statins

14 (20.9%)

61 (32.4%)

0.0751

Antihypertensive medication

43 (64.2%)

123 (65.4%)

0.8541

Antidiabetic therapy

6 (9.0%)

62 (33.0%)

< 0.011

  1. Continuous variables are expressed as mean ± SD or median (interquartile range); categorical variables are presented as numbers and percentage. LVEF, left ventricular ejection fraction. 1P are obtained using the Chi-square test, 2P are obtained using the Mann-Whitney U test and 3P are obtained using Student’s t-test