Molecular epidemiological study of exosomes circZNF609, circPUM1, IGF2 with ischemic stroke

Table 6 Logistic regression analysis of the association between gene expression levels and risk of developing IS

Gene	Group	OR (95%CI)	P	OR (95%CI) ^a	P^a
circZNF609	Q1	reference		reference
	Q2	0.565 (0.318,1.001)	0.050	0.565 (0.315,1.013)	0.035
	Q3	0.437 (0.242,0.788)	0.006	0.416 (0.228,0.761)	0.055
	Q4	0.675 (0.384,1.185)	0.171	0.654 (0.368,1.164)	0.004
circPUM1	Q1	reference		reference
	Q2	0.843 (0.475,1.496)	0.559	0.833 (0.462,1.501)	0.543
	Q3	0.703 (0.392,1.26)	0.237	0.667 (0.366,1.215)	0.185
	Q4	0.782 (0.438,1.395)	0.405	0.773 (0.425,1.404)	0.397
IGF2	Q1	reference		reference
	Q2	0.736 (0.422,1.285)	0.281	0.709 (0.400,1.256)	0.238
	Q3	0.565 (0.319,1.001)	0.050	0.563 (0.313,1.014)	0.056
	Q4	0.565 (0.319,1.001)	0.050	0.543 (0.301,0.978)	0.042

^aAdjusted for age, sex, smoking, alcohol consumption, hypertension, diabetes mellitus, and dyslipidemia; Q1 first quartile(0%−25%), Q2 second quartile(25%−50%), Q3 third quartile(50%−75%), and Q4 fourth quartile(75%−100%)

ISSN: 1471-2261