| Before propensity match weighting | After propensity match weighting | ||||||
---|---|---|---|---|---|---|---|---|
Standard Dose | Underdosing | Overdosing | P-value | Standard Dose | Underdosing | Overdosing | P-value | |
Age, y | 77.58±8.17 | 75.63±9.27 | 79.63±6.48 | 0.147 | 77.55±8.13 | 75.97±9.24 | 82.43±6.05 | 0.018 |
Female, n(%) | 41(49.4%) | 115(55.8%) | 4(50%) | 0.608 | 41(49.4%) | 123(55.2%) | 4(50%) | 0.817 |
Weight | 60.71.19±9.23 | 60.80±11.64 | 63.75±8.55 | 0.751 | 60.64±9.06 | 60.63±11.44 | 63.47±6.93 | 0.387 |
BMI | 23.86±3.14 | 23.74±3.71 | 24.75±2.12 | 0.721 | 23.81±2.98 | 23.71±3.69 | 24.94±1.99 | 0.184 |
Coronary atherosclerotic heart disease | 48(62.3%) | 123(59.7%) | 6(75.0%) | 0.638 | 51(61.4%) | 132(59.2%) | 6(75.0%) | 0.513 |
Heart faliure | 55(71.4%) | 133(64.6%) | 4(50%) | 0.351 | 60(72.3%) | 145(65.0%) | 4(50%) | 0.974 |
Diabetes | 23(29.9%) | 62(30.1%) | 5(62.5%) | 0.176 | 26(31.3%) | 70(31.4%) | 5(62.5%) | 0.491 |
Hypertension | 52(67.5%) | 120(58.3%) | 4(50.0%) | 0.297 | 56(67.5%) | 131(58.7%) | 4(50.0%) | 0.853 |
Cardiomyopathy (dilated cardiomyopathy and hypertrophic cardiomyopathy) | 4(5.2%) | 11(5.3%) | 0(0.0%) | 0.809 | 4(4.8%) | 11(4.9%) | 0(0.0%) | 0.771 |
Renal insufficiency | 8(10.4%) | 8(3.9%) | 2(25.0%) | 0.386 | 10(12.0%) | 9(4.0%) | 2(25.0%) | 0.000 |
Peripheral artery disease | 7(9.1%) | 9(4.4%) | 0(0.0%) | 0.090 | 7(8.4%) | 11(4.9%) | 0(0.0%) | 0.764 |
Anemic | 6(7.8%) | 15(7.3%) | 0(0.0%) | 0.635 | 6(7.2%) | 17(7.6%) | 0(0.0%) | 0.749 |
Hyperthyroidism | 0(0.0%) | 5(2.4%) | 0(0.0%) | 0.272 | 1(1.2%) | 6(2.7%) | 0(0.0%) | 0.464 |
Chronic obstructive pulmonary disease | 13(16.9%) | 24(11.7%) | 1(12.5%) | 0.524 | 13(15.7%) | 26(11.7%) | 1(12.5%) | 0.940 |
Post-PCI | 8(10.4%) | 26(12.6%) | 2(25.0%) | 0.353 | 8(9.6%) | 28(12.6%) | 2(25.0%) | 0.886 |
Previous stroke | 9(11.7%) | 28(13.6%) | 2(25%) | 0.613 | 12(14.5%) | 30(13.5%) | 2(25%) | 0.689 |
Previous-bleeding | 7(9.1%) | 10(4.9%) | 0(0.0%) | 0.127 | 7(8.4%) | 10(4.5%) | 0(0.0%) | 0.771 |
CHA2DAS2-VASc, n(%),(Male:≥2,Female:≥3) | 77(100.0%) | 206(100.0%) | 8(100.0%) | - | 83(100.0%) | 223(100.0%) | 8(100.0%) | - |
HAS-BLED≥3 | 52(67.5%) | 122(59.2%) | 5(62.5%) | 0.436 | 56(67.5%) | 130(58.3%) | 5(62.5%) | 0.817 |