Fig. 2

Change from baseline to endpoint (Week 48) or last observation in left ventricular CMR parameters. Points represent the least squares (LS) mean change with standard error. End systolic volume (A), end diastolic volume (B), cardiac output (C), stroke volume (D), left ventricular mass (E), left ventricular ejection fraction (F). ETD = estimated treatment difference for the difference of tadalafil minus placebo with 95% confidence interval from an analysis of covariance (ANCOVA) with change from baseline as dependent variable, baseline value as covariate, and treatment as fixed effect