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Table 1 Cardiovascular disease characteristics between two groups

From: Association between O-GlcNAc transferase activity and major adverse cardiovascular events: findings from the China PEACE-MPP cohort

Characteristics

Low OGT activity group (n = 973)

High OGT activity group (n = 974)

All (n = 1947)

P

OGT (ng/L)

663.71 ± 165.82

1643.73 ± 887.01

1153.97 ± 804.59

< 0.001

Female, n (%)

460 (47.3%)

547 (56.2%)

1007 (51.7%)

< 0.001

Age (years)

59.46 ± 9.09

59.14 ± 9.21

59.30 ± 9.15

0.623

Smoking, n (%)

177 (18.2%)

141 (14.5%)

318 (16.3%)

0.027

Drinking, n (%)

187 (19.2%)

165 (16.9%)

352 (18.1%)

0.191

Body mass index (kg/m2)

25.28 ± 3.19

24.88 ± 3.2

25.08 ± 3.2

0.564

Obesity, n (%)

183 (18.8%)

148 (15.2%)

331 (17.0%)

0.034

SBP (mmHg)

159.67 ± 19.46

159.17 ± 20.9

159.42 ± 20.19

0.092

High SBP, n (%)

804 (82.6%)

785 (80.6%)

1589 (81.6%)

0.246

DBP (mmHg)

88.10 ± 12.08

87.51 ± 12.41

87.80 ± 12.25

0.257

High DBP, n (%)

430 (44.2%)

426 (43.7%)

856 (44.0%)

0.839

TC (mmol/L)

5.29 ± 1.44

5.53 ± 1.43

5.41 ± 1.44

0.745

Hypercholesterolemia, n (%)

453 (46.6%)

510 (52.4%)

963 (49.5%)

0.010

LDL-c (mmol/L)

2.95 ± 1.19

3.05 ± 1.3

3.00 ± 1.25

0.005

High LDL-c, n (%)

263 (27%)

301 (30.9%)

564 (29.0%)

0.060

HDL-c (mmol/L)

1.37 ± 0.48

1.44 ± 0.46

1.41 ± 0.47

0.175

Low HDL-c, n (%)

263 (27.0%)

183 (18.8%)

446 (22.9%)

< 0.001

TG (mmol/L)

2.41 ± 1.33

2.43 ± 1.33

2.42 ± 1.33

0.574

Hypertriglyceridemia, n (%)

606 (62.3%)

617 (63.3%)

1223 (62.8%)

0.627

Fasting blood glucose (mmol/L)

6.25 ± 2.27

6.17 ± 1.88

6.21 ± 2.08

0.142

Hyperglycemia, n (%)

150 (15.5%)

154 (15.9%)

304 (15.7%)

0.826

History of hypertension, n (%)

438 (45%)

428 (43.9%)

866 (44.5%)

0.634

History of diabetes, n (%)

120 (12.3%)

103 (10.6%)

223 (11.5%)

0.223

History of AMI, n (%)

7 (0.7%)

12 (1.2%)

19 (1.0%)

0.250

History of stroke, n (%)

60 (6.2%)

47 (4.8%)

107 (5.5%)

0.194

History of cardiovascular and cerebrovascular disease, n (%)

89 (9.1%)

72 (7.4%)

161 (8.3%)

0.160

  1. OGT: O-GlcNAc transferase; TC: total cholesterol; LDL-c: low-density lipoprotein cholesterol; HDL-c: high-density lipoprotein cholesterol; TG: triglycerides; FBS: fasting blood glucose; AMI: acute myocardial infarction; SBP: systolic blood pressure; DBP: diastolic blood pressure
  2. High SBP: SBP ≥ 140 mmHg; high DBP: DBP ≥ 90 mmHg; hypercholesterolemia: TC ≥ 5.2 mmol/L; high LDL-c: LDL-c ≥ 3.4 mmol/L; low HDL-c: HDL-c < 1.04 mmol/L; hypertriglyceridemia: TG ≥ 1.7 mmol/L; hyperglycemia: fasting blood glucose ≥ 7.0 mmol/L; obesity: BMI ≥ 28 kg/m2