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Fig. 4 | BMC Cardiovascular Disorders

Fig. 4

From: Alkbh5 promotes Ythdf1 expression through demethylation thereby facilitating Fth1 translation to inhibit ferroptosis of myocardial infarction

Fig. 4

Alkbh5-mediated m6A demethylation promotes the expression of Ythdf1. (A) The m6A level of Ythdf1 was measured by MeRIP. (B and C) The expression of Ythdf1 was measured by qPCR. (D) The potential m6A site in Ythdf1 was predicted using the SRAMP database. (E) The stability of Ythdf1 mRNA was measured by qPCR after H9C2 cells treated with 5 µg/mL actinomycin D treatment for 0, 4, 8 and 12 h. (F) Ythdf1 expression in H9C2 cells was measured by qPCR. (G) The binding between Fth1 and Ythdf1 was measured by RIP

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BMC Cardiovascular Disorders

ISSN: 1471-2261

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