Table 1 Baseline characteristics of the study subjects
| Â | PAD group (N=105) | Controls (N=373) | p value |
|---|---|---|---|
General information | Â | Â | Â |
 Gender |  |  |  |
 Female (n/%) | 23 (21.9) | 106 (28.4) | 0.184 |
 Male (n/%) | 82 (78.1) | 367 (71.6) |  |
 Age (years) | 65 (57,70) | 62 (53,70) | 0.045 |
 BMI (kg/m2) | 24.2 (22.5,26.7) | 24.3 (22.0,27.2) | 0.893 |
History of diseases and smoking | Â | Â | Â |
 Coronary artery disease (n/%) | 33 (31.4) | 139 (37.3) | 0.271 |
 Stroke (n/%) | 11 (10.5) | 28 (7.5) | 0.326 |
 HTN (n/%) | 71 (67.6) | 216 (57.9) | 0.029 |
 DM (n/%) | 53 (50.5) | 112 (30.0) | <0.001 |
 Smoking (n/%) | 53 (50.5) | 163 (43.7) | 0.218 |
Laboratory indicators | Â | Â | Â |
 WBC (*109) | 7.27 (5.83,8.91) | 7.41 (5.86,9.13) | 0.825 |
 Creatinine (μmol/L) | 80.50 (65.96,93.45) | 75.35 (63.53,89.52) | 0.111 |
 eGFR[ml/ (min*1.73m2)] | 87.50 (73.25,106.50) | 93.50 (76.00,107.00) | 0.224 |
 TC (mmol/L) | 4.77 (3.86,6.10) | 4.82 (4.06,5.72) | 0.736 |
 TG (mmol/L) | 1.43 (1.02,1.90) | 1.48 (1.07,2.11) | 0.485 |
 LDL-C (mmol/L) | 2.78 (1.98,3.66) | 2.96 (2.32,3.71) | 0.131 |
 HDL-C (mmol/L) | 1.11 (0.94,1.32) | 1.16 (0.98,1.39) | 0.047 |
 HA1c (%) | 7.90 (7.20,9.00) | 7.50 (6.20,8.70) | 0.030 |
 S100A8/A9 (ng/cL) | 0.10 (0.06,0.94) | 0.09 (0.06,0.14) | 0.069 |
 S100A12 (ng/cL) | 0.22 (0.13,1.49) | 0.13 (0.10,0.18) | <0.001 |