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Fig. 7 | BMC Cardiovascular Disorders

Fig. 7

From: Combining genetic proxies of drug targets and time-to-event analyses from longitudinal observational data to identify target patient populations

Fig. 7

Effect of GLP1R rs10305492 on time to HF hospitalization or cardiovascular (CV) death/heart transplant composite outcome from first ischemic heart disease diagnosis (IHD) in (a) unmatched and (b) matched participants. Individuals with GA/AA genotypes (proxy for GLP1-R agonist treatment) showed reduced risk of HF hospitalization composite outcome compared to individuals with GG genotype (controls). *Didn’t meet proportional hazard assumption, P calculated with Gehan-Breslow test

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BMC Cardiovascular Disorders

ISSN: 1471-2261

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