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Table 4 Cardiovascular maces and bleeding

From: Protective effects of combined eptifibatide and ticagrelor in patients with unstable angina undergoing percutaneous coronary intervention: a single-center experience

Endpoints

Eptifibatide + ticagrelor

Ticagrelor

P value

(n = 152)

(n = 152)

In-hospital MACEs

   

 All-cause mortality

0 (0%)

1 (0.66%)

0.317

 MI (types 1 and 4)

9 (5.92%)

20 (13.15%)

0.032*

 TVR

1 (0.66%)

3 (1.97%)

0.314

 Stent thrombosis

1 (0.66%)

0 (0%)

0.317

 Stroke/TIA

1 (0.66%)

2 (1.31%)

0.562

 Overall MACEs

12 (7.89%)

26 (17.12%)

0.015*

12-month MACEs

   

 All-cause mortality

2 (1.31%)

2 (1.31%)

1

 MI (types 1 and 4)

15 (9.87%)

28 (18.42%)

0.032*

 TVR

5 (3.29%)

6 (3.94%)

0.759

 Stent thrombosis

1 (0.66%)

0 (0%)

0.317

 Stroke/TIA

3 (1.97%)

2 (1.31%)

0.652

 Overall MACEs

26 (17.11%)

38 (25%)

0.091

In-hospital bleeding

   

 Major bleeding

1 (0.66%)

1 (0.66%)

1

 Minor bleeding

29 (19.08%)

26 (17.11%)

0.655

 Any bleeding

30 (19.74%)

27 (17.76%)

0.659

12-month bleeding

   

 Major bleeding

4 (2.63%)

3 (1.97%)

0.702

 Minor bleeding

38 (25%)

35 (23.02%)

0.687

 Any bleeding

42 (27.63%)

38 (25%)

0.602

  1. *P < 0.05 eptifibatide + ticagrelor vs. ticagrelor. The data are presented as n (%). MACEs: major adverse cardiovascular events; MI: myocardial infarction; TIA: transient ischemic attack; TVR: target vessel revascularization