Fig. 1

Schematic representation of the CYP2C19 gene location, structure, studied SNPs, and primer positions. (a) Human chromosome 10 with the 10q.23.33 band marked by a red vertical line. (b) A cluster of four cytochrome P450 genes including CYP2C18, CYP2C19, CYP2C9, and CYP2C8. (c) Core sequence variations defining CYP2C19*2, *3 and, *17 alleles. (d) Targeted locations of the forward and reverse primers for each of the studied SNPs. Forward and reverse primers are represented by green and yellow arrows, respectively. The arrow’s tip indicates the 5′➔3’ orientation of the primers. The dotted lines depict the PCR product lengths for each primer set