Table 4 Observed versus expected genotype distribution of CYP2C19
Phenotype | N (%) | Genotype | N (%) Observed | N (%) Expected | HWE x2 | HWE P value |
|---|---|---|---|---|---|---|
UMs | 2 (4%) | *17/*17 | 2 (4%) | 1.44 (2.89%) | 0.2131 | 0.64 |
RMs | 13 (26%) | *1/*17 | 13 (26%) | 12.75 (25.5%) | 0.0049 | 0.94 |
NMs | 28 (56%) | *1/*1 | 28 (56%) | 28.13 (56.25%) | 0.00055 | 0.98 |
IMs | 6 (12%) | *1/*2 | 6 (12%) | 6 (12%) | 0 | 1 |
*1/*3 | 0 (0%) | 0 (0%) | NA | NA | ||
*17/*2 | 0 (0%) | 1.36 (2.72%) | 1.36 | 0.24 | ||
*17/*3 | 0 (0%) | 0 (0%) | NA | NA | ||
PMs | 1 (2%) | *2/*2 | 1 (2%) | 0.32 (0.64%) | 1.445 | 0.22 |
*2/*3 | 0 (0%) | 0 (0%) | NA | NA | ||
*3/*3 | 0 (0%) | 0 (0%) | NA | NA |