Table 1 Baseline characteristics of weighted participants
Characteristic | Hemoglobin-albumin-lymphocyte-platelet score | P | |||
|---|---|---|---|---|---|
Q1 Weighted N = 55,509,646 Unweighted n = 1,7171 | Q2 Weighted N = 62,645,900 Unweighted n = 1,7151 | Q3 Weighted N = 59,870,976 Unweighted n = 1,7191 | Q4 Weighted N = 60,506,572 Unweighted n = 1,7181 | ||
Age | 59 ± 15 | 58 ± 14 | 56 ± 14 | 56 ± 14 | < 0.0011 |
BMI | 33 ± 9 | 33 ± 8 | 33 ± 7 | 32 ± 7 | 0.5011 |
PIR | 2.46 (1.31, 4.56) | 2.92 (1.46, 5.00) | 3.06 (1.49, 5.00) | 2.64 (1.34, 4.60) | < 0.0012 |
HbA1c | 6.30 (5.70, 7.00) | 6.20 (5.70, 7.10) | 6.30 (5.70, 7.30) | 6.40 (5.70, 7.50) | 0.0612 |
Aspartate Aminotransferase (U/L) | 22 (18, 26) | 23 (19, 27) | 23 (19, 28) | 24 (20, 31) | < 0.0012 |
Alanine Aminotransferase (U/L) | 19 (15, 26) | 22 (17, 29) | 24 (18, 32) | 25 (19, 35) | < 0.0012 |
Gamma Glutamyl Transferase (IU/L) | 20 (14, 33) | 22 (16, 33) | 25 (17, 38) | 27 (18, 42) | < 0.0012 |
Total protein (g/dL) | 7.00 ± 0.51 | 7.05 ± 0.46 | 7.11 ± 0.44 | 7.16 ± 0.46 | < 0.0011 |
Triglycerides (mg/dL) | 135 (92, 197) | 141 (94, 215) | 158 (108, 229) | 172 (113, 255) | < 0.0012 |
Cholesterol (mg/dL) | 185 ± 51 | 188 ± 43 | 191 ± 44 | 189 ± 45 | 0.0071 |
HDL-C (mmol/L) | 1.33 ± 0.39 | 1.30 ± 0.37 | 1.26 ± 0.42 | 1.18 ± 0.34 | < 0.0011 |
Serum creatinine (mg/dL) | 0.87 (0.72, 1.10) | 0.86 (0.71, 1.02) | 0.86 (0.73, 1.01) | 0.89 (0.75, 1.02) | 0.1402 |
Blood Urea Nitrogen (mg/dL) | 15 (11, 20) | 14 (11, 18) | 14 (11, 18) | 14 (11, 18) | 0.0282 |
Uric acid (mg/dL) | 5.66 ± 1.67 | 5.62 ± 1.50 | 5.72 ± 1.41 | 5.75 ± 1.43 | 0.0461 |
Total Bilirubin (mg/dL) | 0.60 (0.40, 0.70) | 0.60 (0.40, 0.80) | 0.60 (0.40, 0.80) | 0.60 (0.40, 0.80) | < 0.0012 |
Lactate Dehydrogenase (IU/L) | 138 (119, 161) | 133 (116, 153) | 131 (115, 150) | 134 (116, 153) | 0.0022 |
Gender | < 0.0013 | ||||
Female | 37.0% | 44.3% | 50.4% | 65.0% | |
Male | 63.0% | 55.7% | 49.6% | 35.0% | |
Race | < 0.0013 | ||||
Mexican American | 6.8% | 7.7% | 9.3% | 11.0% | |
Other Hispanic | 5.2% | 5.4% | 6.3% | 5.7% | |
Non-Hispanic White | 62.9% | 66.9% | 63.9% | 63.5% | |
Non-Hispanic Black | 17.6% | 11.5% | 11.7% | 10.8% | |
Other Race | 7.5% | 8.5% | 8.7% | 8.9% | |
Drinking status | < 0.0013 | ||||
Not at all | 14.6% | 12.9% | 10.5% | 11.0% | |
Former | 23.2% | 20.6% | 21.1% | 18.6% | |
Mild | 33.0% | 32.3% | 33.2% | 29.3% | |
Moderate | 8.1% | 12.2% | 11.3% | 8.9% | |
Severe | 21.1% | 22.1% | 23.9% | 32.2% | |
Smoking status | < 0.0013 | ||||
Not at all | 52.1% | 55.5% | 49.7% | 44.0% | |
Former | 36.0% | 33.9% | 33.9% | 31.7% | |
Now | 11.9% | 10.6% | 16.4% | 24.3% | |
Education levels | 0.0733 | ||||
Less than high school | 19.9% | 17.1% | 18.9% | 20.6% | |
High school or Some College or AA degree | 56.7% | 55.0% | 55.3% | 57.5% | |
College Graduate above | 23.4% | 27.9% | 25.8% | 21.9% | |
Married status | 0.0873 | ||||
Married/Living with partner | 50.4% | 55.7% | 58.2% | 54.9% | |
Widowed/Divorced/Separated | 41.7% | 37.4% | 34.4% | 36.9% | |
Never Married | 8.0% | 6.9% | 7.4% | 8.2% | |
Hypertension | 0.1303 | ||||
With hypertension | 63.2% | 59.8% | 57.4% | 58.2% | |
Without hypertension | 36.8% | 40.2% | 42.6% | 41.8% | |
All-cause mortality | < 0.0013 | ||||
Survival | 77.2% | 87.5% | 87.7% | 89.0% | |
Death | 22.8% | 12.5% | 12.3% | 11.0% | |
Carviovascular mortality | < 0.0013 | ||||
Survival | 91.7% | 96.9% | 95.6% | 96.8% | |
Death | 8.3% | 3.1% | 4.4% | 3.2% | |
Prediabetes or Diabetes | 0.0023 | ||||
Prediabetes | 24.5% | 30.7% | 30.7% | 24.9% | |
Diabetes | 75.5% | 69.3% | 69.3% | 75.1% | |