Fig. 9
From: The relevance of resveratrol in ameliorating carotid atherosclerosis through glycolysis
The effect of Res on the PI3K/Akt signaling pathway in ox-LDL-induced HUVECs. a HUVECs were treated with res at concentrations of 0.25, 0.5, and 1 μM for 24 h; The levels of PI3K, AKT, and their phosphorylated forms were detected in protein samples using WB. b Cells were treated with the AKT inhibitor LY294002, and the levels of p-AKT were detected using WB. c Levels of the key enzyme of glycolysis (HK2, GLUT1, and PFKFB) after addition of the inhibitor. All data are presented as the mean ± SD, one-way ANOVA, n ≥ 6 per group, *P < 0.05, **P < 0.01, ***P < 0.001