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  1. To investigate the differential expression of soluble suppression of tumorigenicity 2 (sST2) in patients with coronary artery disease (CAD) and healthy controls, and the correlation between sST2 and the severi...

    Authors: Shuai Zhang, Lu Qian, Shibao Li and Zhijian Liu
    Citation: BMC Cardiovascular Disorders 2025 25:334
  2. Atherosclerosis is a major contributor to cardiovascular disease, and dyslipidemia, particularly low-density lipoprotein cholesterol (LDL-C)/ high-density lipoprotein cholesterol (HDL-C) ratio, plays a critica...

    Authors: Yan Jiang, Lina Zhang and Zhifeng Gu
    Citation: BMC Cardiovascular Disorders 2025 25:333
  3. Genetic variations in the CYP2C19 gene, which encodes the major enzyme responsible for activating clopidogrel, may influence response to Clopidogrel antiplatelet therapy. This study aimed to assess the prevalence...

    Authors: Nour Haj Saleh and Lama A. Youssef
    Citation: BMC Cardiovascular Disorders 2025 25:330
  4. This study aims to explore the temporal relationship between ischemic J waves and the progression of chest discomfort in patients experiencing acute myocardial infarction (AMI) during its earliest phase.

    Authors: Huanhuan Hu, Lu Huang, Dewen Zhu, Mingwei Wang, Deye Yang, Hongyu Wang and Lina Chen
    Citation: BMC Cardiovascular Disorders 2025 25:328
  5. The existing evidence regarding the relationship between the triglyceride-glucose index (TyG index) and cardiovascular mortality risk remains relatively limited and controversial, particularly within the conte...

    Authors: Jianchun Yao, Jinping Lu, Linfen Li and Liangping Huang
    Citation: BMC Cardiovascular Disorders 2025 25:326
  6. Coronary artery disease is the most prevalent heart condition and a leading cause of mortality worldwide. Acute coronary syndrome (ACS) encompasses ST-elevation myocardial infarction (STEMI), non-ST elevation ...

    Authors: Chempay, Yeshey Dorjey, Ugyen Tshering and Melanie R. Watts
    Citation: BMC Cardiovascular Disorders 2025 25:324
  7. The purpose of this study was to assess the relationship between admission inflammatory indexes neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), and systemic immune-inflammation index ...

    Authors: Yijing Xin, Siqi Lyu, Jingyang Wang, Yimeng Wang, Yuyuan Shu, Hanyang Liang and Yanmin Yang
    Citation: BMC Cardiovascular Disorders 2025 25:323
  8. This study aimed to assess the effects of distal transradial access (dTRA) compared to conventional transradial access (cTRA) on procedure duration and radiation exposure among patients undergoing carotid arte...

    Authors: Li-feng Wang, Xu Guo, Zhe Song, Xiao-fen He, Xia Ma and Xiao-ping Zhang
    Citation: BMC Cardiovascular Disorders 2025 25:321
  9. A retrospective analysis of patients with descending necrotizing mediastinum (DNM) admitted to the emergency department was performed to improve emergency physicians’ knowledge of DNM, so as to achieve early j...

    Authors: Fangfang Deng, Anyong Yu, Cui Yang, Guangli Yang, Dandan Zhou, Xiaogang Nie, Wenxin Luo and Tianxi Zhang
    Citation: BMC Cardiovascular Disorders 2025 25:320
  10. ICI-associated myocarditis is an uncommon yet potentially fatal condition, particularly when concomitant with atrioventricular block (AVB) necessitating pacing. The role of pacing therapy for ICI-associated AV...

    Authors: Jiaqi Wang, Fanyi Kong, Yifan Wang, Jiaqi Yu, Yingxian Liu, Wei Wu, Yongtai Liu, Peng Gao, Zhongwei Cheng, Kang’an Cheng, Hua Deng, Jinzhi Lai, Jingbo Fan, Lihua Zhang, Quan Fang, Taibo Chen…
    Citation: BMC Cardiovascular Disorders 2025 25:319
  11. Systemic inflammation contributes to the progression of heart failure (HF). This study aims to investigate the association between inflammatory burden index (IBI) and HF risk.

    Authors: Li-Xin Yun, Wan-Zhong Huang, Changjing He, Yuan Huang, Hua-Feng Yang, Qiang Su, Da-Zhi Lan and Yang-Chun Liu
    Citation: BMC Cardiovascular Disorders 2025 25:318
  12. Heart failure (HF) is a major cause of mortality in critically ill patients and often requires intensive care. The hemoglobin glycation index (HGI), defined as the difference between predicted glycated hemoglo...

    Authors: Yulong Wang, Shanshan Tang, Haokun Liu and Yongle Li
    Citation: BMC Cardiovascular Disorders 2025 25:317
  13. Postoperative atrial fibrillation (POAF) is a common complication after off-pump coronary artery bypass grafting (OPCABG), associated with increased morbidity and healthcare costs. Existing POAF prediction mod...

    Authors: Yihan Zheng, Min Zhou, Yiting Lin and Guican Zhang
    Citation: BMC Cardiovascular Disorders 2025 25:316
  14. Managing recurrent atrial flutter (AFL) following radiofrequency ablation (RFA) for atrial fibrillation (AF) poses significant clinical challenges.

    Authors: Zikan Zhong, Xiaoyu Wu, Jie An, Qitong Zhang, Cheng Cheng, Yong Wei, Songwen Chen, Shaowen Liu and Genqing Zhou
    Citation: BMC Cardiovascular Disorders 2025 25:315

    The Correction to this article has been published in BMC Cardiovascular Disorders 2025 25:382

  15. Cardiovascular diseases are the leading cause of mortality in the United States, presenting significant public health challenges and financial burdens, particularly in Southeastern Virginia, where African Amer...

    Authors: El Moudden Ismail, Amidi Asra, Sharaf Alddin Reem, Bittner Michael and Zhang Qi
    Citation: BMC Cardiovascular Disorders 2025 25:314
  16. S100A12 acts as a pro-inflammatory agent in vivo, with a close relationship with plaque formation in patients with acute coronary syndrome (ACS), end-stage renal disease, and diabetes. Peripheral arterial dise...

    Authors: Wenyu Cai, Yilin He, Guohua Li, Dengqing Zhang, Zimin Chen, Shijia Jin, Yifan Zhang and Zhong Chen
    Citation: BMC Cardiovascular Disorders 2025 25:313
  17. We evaluated the safety and effectiveness of combined eptifibatide and ticagrelor in patients with unstable angina pectoris undergoing percutaneous coronary intervention (PCI).

    Authors: Shangsong Shi, Zicheng Ling, Shaohua Gu, Tingbo Jiang and Lin Ling
    Citation: BMC Cardiovascular Disorders 2025 25:312
  18. The coronary lumen volume to myocardial mass (V/M) ratio has been suggested as a quantitative metric of potential imbalance between coronary blood supply and myocardial oxygen demand. This study was designed t...

    Authors: Wenting Li, Ruichen Ren, Qingyuan Zhao, Chengcheng Qi, Zhiyu Chen and Yang Zhang
    Citation: BMC Cardiovascular Disorders 2025 25:311
  19. Percutaneous coronary intervention (PCI) has been the main treatment of coronary artery disease (CAD). In this review, we aimed to compare the performance of machine learning (ML) vs. logistic regression (LR) ...

    Authors: Sepehr Nayebirad, Ali Hassanzadeh, Amir Mohammad Vahdani, Aida Mohamadi, Shayan Forghani, Akbar Shafiee and Farzad Masoudkabir
    Citation: BMC Cardiovascular Disorders 2025 25:310
  20. Firefighting involves exposure to hazardous conditions that may contribute to adverse long term health outcomes, including cardiovascular disease. While coronary artery disease (CAD) is a leading cause of morb...

    Authors: Mingyue Li, Jiali Han, Carolyn Muegge, Terrell Zollinger, Laura Y. Zhou, Patrick Monahan, Jennifer Wessel, Vanessa Kleinschmidt, Steven Moffatt and Hongmei Nan
    Citation: BMC Cardiovascular Disorders 2025 25:309
  21. The high prevalence of atrial fibrillation (AF) and obstructive sleep apnea syndrome (OSAS) imposes a substantial disease burden on public healthcare, making it a significant health concern in the current era....

    Authors: Xiaoting Zhang, Meng Wei, Pengjie Xue, Yanmei Lu and Baopeng Tang
    Citation: BMC Cardiovascular Disorders 2025 25:308
  22. Heart failure (HF) is a chronic progressive syndrome caused by a variety of cardiovascular diseases and is associated with high morbidity, mortality, and healthcare burden. Forecasting the prognosis of HF pati...

    Authors: Xiaopo Gao, Cheng Li, Yurou Wang, Yun Cu, Yingfang Zheng, Hongkai Dai, Xinrun Yuan, Jinlong Luo and Chengye Zhan
    Citation: BMC Cardiovascular Disorders 2025 25:307
  23. New-onset postoperative atrial fibrillation (POAF) is common after transcatheter aortic valve replacement (TAVR). At present, the impact of POAF on cardiac remodeling after TAVR has not been thoroughly studied.

    Authors: Hua-Jie Zheng, Jun Li, Ling-Feng Tang, Mei Guo, Ya-Nan Wei and Wei Cheng
    Citation: BMC Cardiovascular Disorders 2025 25:306
  24. To evaluate the efficacy of negative-pressure wound therapy (NPWT) for cardiac implantable electronic device (CIED) pocket infection, eliminating the need for CIED and leads extraction.

    Authors: Genmiao Yu, Xiongmei Huang, Rongjia Lin and Shengwu Zheng
    Citation: BMC Cardiovascular Disorders 2025 25:305
  25. Left atrial appendage closure (LAAC) has become the treatment of choice for stroke prevention in patients with nonvalvular atrial fibrillation who are at high risk of bleeding or with contraindications for ant...

    Authors: Xuan Lu, Zhenyu Yang, Wei Fang, Xiaona Niu, Qiuhe Wang and Yan Li
    Citation: BMC Cardiovascular Disorders 2025 25:304
  26. Patients with atrial fibrillation (AF) may benefit from PLAAO, a method proven to reduce the risk of stroke. However, the risk of requiring blood transfusion during the perioperative period has not been adequa...

    Authors: Binbin Tian, Chunbo Chen, Chengzhao Huang, Qiuqiang Chen, Junfen Cheng, Haiqiang Wu, Jian Wang, Junde Mo, Guorong Zhong and Xiaozhuo Chen
    Citation: BMC Cardiovascular Disorders 2025 25:303
  27. Heart failure (HF) in Sub-Saharan Africa (SSA) presents unique challenges, with high prevalence and distinct epidemiological features compared to high-income settings. Despite its burden, recent comprehensive ...

    Authors: Djibrilla Siddikatou, Edgar Mandeng Ma Linwa, Valérie Ndobo, Clovis Nkoke, Sidick Mouliom, Marie Solange Ndom, Ali Abas and Félicité Kamdem
    Citation: BMC Cardiovascular Disorders 2025 25:302
  28. Atherosclerosis (AS) poses a pressing challenge in contemporary medicine. Glycolysis is a crucial bioenergetic metabolic pathway that provides the primary energy source for endothelial cells. Resveratrol (Res)...

    Authors: Henan Pan, Zongkai Wu, Yaran Gao, Wentao Yao, Ge Feng and Hebo Wang
    Citation: BMC Cardiovascular Disorders 2025 25:301
  29. This study investigates the diagnostic value of transesophageal echocardiography (TEE) for assessing the left atrial appendage (LAA) in patients with patent foramen ovale (PFO) and atrial fibrillation (AF). TE...

    Authors: Zhaojun Zhang, Yu Zhu, Guangmei Zheng, Hongxia Jing, Bin Xiao and Lin Xiong
    Citation: BMC Cardiovascular Disorders 2025 25:300
  30. Standardized tools are needed to accurately assess the severity of postoperative complications in cardiac surgery, which is critical for patient management and outcome evaluation. This study aims to evaluate t...

    Authors: Zhen-Rong Zhang, Yang-Zheng Li, Xiao-Qing Wu, Wen-Jun Chen, Jie-Yang Yuan and Min Yan
    Citation: BMC Cardiovascular Disorders 2025 25:299
  31. Inflammatory mediators and immune activation can intensify the inflammatory response within atherosclerotic plaques, increasing the risk of plaque rupture and thrombosis. This study aims to compare peri-corona...

    Authors: Yanglei Li, Chen Wang, Qinyue Wang, Siqi Li, Junchao Yang, Hanqin Pan, Ming Li, Xinkai Qu, Yiran Qin, Chunwei Ma, Lin Qi, Mingxuan Li and Kailei Shi
    Citation: BMC Cardiovascular Disorders 2025 25:298
  32. Pulse pressure has been commonly used to assess atherosclerosis and cardiovascular outcomes with the defects of fluctuation. However, the pulse pressure index (PPI), a feasible alternative with the advantage o...

    Authors: Luo-Xiang Fang, Yi-Hao Wu, Tao Yao, Zhe-Ning Wang, Sang Qian, Ting Jiang, Jing Xu, Yuan-Nan Lin and Yue-Chun Li
    Citation: BMC Cardiovascular Disorders 2025 25:297
  33. Transthyretin (TTR) Cardiomyopathy (ATTR-CM) is characterized by the deposition of misfolded TTR monomers in the heart, leading to progressive heart failure. TTR-specific therapies offer a pharmacological appr...

    Authors: Alonzo Armani Prata, Eric Shih Katsuyama, Pedro Gabriel Scardini, Ana Carolina Covre, Wilson Falco Neto, Julia Marques Fernandes, Gabriel Scarpioni Barbosa, Chris Fukunaga, Rafael Petri Pinheiro, Vanio L. J. Antunes, Luciana Gioli-Pereira and Fabio Fernandes
    Citation: BMC Cardiovascular Disorders 2025 25:296
  34. Myocardial infarction (MI) is a leading cause of global mortality. Ferroptosis, an iron-dependent form of programmed cell death, has recently emerged as a critical player in cardiovascular diseases. N6-methyla...

    Authors: Mingnan Yin and Heping Liu
    Citation: BMC Cardiovascular Disorders 2025 25:295
  35. In light of the well-established connection between sympathetic overactivity and early adverse events in myocardial infarction (MI) patients, this study aims to explore the potential association between serum ...

    Authors: Marijana Mikacic, Marko Kumric, Iva Rancic Vidic, Duska Glavas, Tina Ticinovic Kurir, Josko Bozic and Josip Andelo Borovac
    Citation: BMC Cardiovascular Disorders 2025 25:294
  36. We aimed to explore the correlation between epicardial fat volume (EFV) and the severity of coronary atherosclerotic artery disease (CAD), evaluate the predictive value of EFV for obstructive CAD, and provide ...

    Authors: Hangyi Zhou, Yuxin Pan, Juan Du, Fen Liang, Xiaojun Ma and Dongling Lv
    Citation: BMC Cardiovascular Disorders 2025 25:293
  37. The Metabolic Vulnerability Index (MVX) is a novel multi-marker risk score derived from nuclear magnetic resonance (NMR) measures and has shown predictive value for mortality in heart failure. Hence, we aimed ...

    Authors: Kayode O. Kuku, Joseph J. Shearer, Jungnam Joo, Alan T. Remaley, Margery A. Connelly, Suzette J. Bielinski and Véronique L. Roger
    Citation: BMC Cardiovascular Disorders 2025 25:292
  38. This study aims to compare the efficacy of different mind-body exercises (MBEs) on cardiometabolic risk factors in patients with type 2 diabetes mellitus (T2DM) using a network meta-analysis of randomized cont...

    Authors: Xi Li, Menglong Gao and Jiao Hua
    Citation: BMC Cardiovascular Disorders 2025 25:291
  39. Cardiovascular disease (CVD) is the leading cause of death worldwide. Risk stratification of CVD patients may be improved by predictive biomarkers, including genetic markers. Elevated circulating vascular endo...

    Authors: J. C. Meza-Alvarado, A. P. Pilbrow, C. M. Frampton, V. A. Cameron, A. M. Richards, R. W. Troughton, R. N. Doughty, R. A. Page, B. Mallard, C. Bromhead and B. R. Palmer
    Citation: BMC Cardiovascular Disorders 2025 25:290
  40. The Hepatic Steatosis Index (HSI) serves as a non-invasive indicator for assessing liver fat accumulation. Its potential association with hypertension has garnered increasing attention, as metabolic dysfunctio...

    Authors: Wenxuan Zhang, Bing Gao, Yaping Wang, Yuxiang Cao and Jing Wang
    Citation: BMC Cardiovascular Disorders 2025 25:289
  41. Respiratory rate (RR) is one important vital sign that is often neglected in patients with acute myocardial infarction (AMI). The present study aimed to evaluate the impact of admission RR on the prognosis in ...

    Authors: Bryan Richard Sasmita, Siyuan Xie, Linfeng Xie, Jing Chen, Jian Shen, Xiang Li, Gang Liu, Yuan Yang, Yintao Chen, Suxin Luo and Bi Huang
    Citation: BMC Cardiovascular Disorders 2025 25:288
  42. Concurrent anemia is associated with an increased risk of major adverse cardiac events (MACE) in patients with myocardial infarction. The study aimed to assess the value of anemia and preoperative hemoglobin l...

    Authors: Hailang Liu, Chunyang Yu, Tingting Hu, Zhongcheng Wei, Jin Geng and Xiwen Zhang
    Citation: BMC Cardiovascular Disorders 2025 25:287
  43. The axillary vein approach has emerged as a promising alternative to subclavian venous access for pacemaker implantation, offering potential advantages including reduced infection risk and enhanced procedural ...

    Authors: Bing Ji, Yu Mao, Xue-Bo Liu, Bing Sun and Yuan Xie
    Citation: BMC Cardiovascular Disorders 2025 25:286
  44. Patients with atrial fibrillation (AF) often underwent percutaneous coronary intervention (PCI), and the complexity of PCI has risen in recent years. However, there is limited data available on clinical outcom...

    Authors: Yimeng Wang, Han Zhang, Jiang-shan Tan, Lulu Wang, Jingyang Wang, Yuyuan Shu and Yanmin Yang
    Citation: BMC Cardiovascular Disorders 2025 25:285
  45. Physical frailty is highly prevalent in heart failure (HF), but we lack an understanding of the underlying pathophysiology. Proteomic evaluation of plasma samples may elucidate potential mechanisms and biomark...

    Authors: Quin E. Denfeld, Noelle V. Pavlovic, Christopher S. Lee, Jon M. Jacobs, Mary Roberts Davis, Samantha M. Powell, Marina Gritsenko, Susan M. Joseph and Beth A. Habecker
    Citation: BMC Cardiovascular Disorders 2025 25:284
  46. The O-GlcNAc transferase (OGT) levels are closely related to the O-GlcNAcylation of proteins and are also associated with cardiovascular disease. This study explored the association between OGT activity and ma...

    Authors: Wei Yu, Shiyun Hu, Xiaoling Xu, Jianlin Shao, Jing Yan and Fang Ding
    Citation: BMC Cardiovascular Disorders 2025 25:281

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